Somatrop-Lab Clomiphene Citrate 50 tabs (50 mg/tab)

Clomiphene Citrate – Clomid

Clomiphene citrate, known as Clomid, is a synthetic, non-steroidal medication closely resembling estrogen. This drug serves primarily as an ovulatory stimulant, leveraging its structural similarity to bind with estrogen receptors in the hypothalamus. Consequently, this action obstructs the hypothalamus from detecting natural estrogen levels, inciting the pituitary gland to release increased quantities of gonadotropins, such as FSH and LH, which in turn encourage the ovaries or testes to produce enhanced levels of estrogen or testosterone. Clomiphene’s functionality has made it invaluable for treating women experiencing ovarian failure and the need for ovulation induction. Nonetheless, prolonged administration of Clomid may carry risks, including a heightened chance of ovarian cancer.

Pharmacology

Clomid is typically prescribed for women facing ovulatory dysfunction. Many women struggling with infertility exhibit irregularities in the ovulation cycle. Individuals with conditions such as polycystic ovarian syndrome or unexplained amenorrhea may also benefit. A thorough menstrual cycle evaluation is critical prior to prescribing Clomid to pinpoint the issue. Effective ovulation treatment necessitates precise timing, including monitoring body temperature and conducting blood tests to confirm ovulation. Typically initiated around day 5 of the menstrual cycle, Clomid is administered for 3 to 6 cycles, as long-term therapy is discouraged.

Mode of Action

Clomid is a potent medication when administered judiciously and for brief durations, particularly benefiting women grappling with infertility. By mimicking estrogen, clomiphene interacts with estrogen receptors in the hypothalamus, leading the brain to perceive low estrone levels, which escalate gonadotropin release, thus stimulating ovarian estrogen production. This rise in estrogen is crucial for facilitating fertilization.

Indications

Clomid is approved solely for women experiencing ovulatory dysfunction under specific conditions:

• the patient is not pregnant
• ultrasound confirms the absence of ovarian cysts
• no vaginal bleeding is present; if bleeding occurs, a comprehensive examination is mandated
• normal liver function tests are essential
• although Clomid has shown success in women, its efficacy for male infertility is less studied, despite some instances of LH and FSH surge leading to increased sperm count.

Clomiphene, a large molecule soluble in various organic solvents, is available in 50 mg tablet form. Candidates for Clomid must complete evaluations for all gynecological and endocrine disorders. Ovulation generally occurs 5-10 days after initiation, necessitating timed intercourse to maximize chances of conception. The treatment typically commences with a 50 mg daily dose for 5 days, adjustable for non-responding females.

Body Building

Clomid is frequently misused by athletes, both amateur and professional, alongside other substances such as anabolic steroids and HCG. Unlike anabolic alternatives, Clomid can elevate testosterone levels due to its stimulation of LH release. While many anabolic steroids boast both anabolic and androgenic properties, some convert to estrogen via aromatization, leading to gynecomastia—a concern for bodybuilders. Thus, Clomid serves to prevent this condition by blocking estrogen receptors. Furthermore, the hormonal surge facilitated by Clomid enhances testosterone production, providing an additional advantage for athletes.

Clomid Dosage for Athletes

Usage instructions dictate Clomid be taken once daily, often either solo or in conjunction with low-potency anabolic steroids. Athletes typically cycle from anabolic steroids to Clomid, initiating the latter 7-10 days post-steroid cessation to induce testosterone surges while averting breast enlargement. Dosing among bodybuilders varies significantly; many consume between 50-100 mg/day for two weeks. Adjustments may occur if no effects are perceived, but usage beyond the third week is discouraged due to the absence of clinical guidelines.

Side Effects

When taken as prescribed for short periods, Clomid is generally well-tolerated, with most side effects disappearing upon discontinuation. Common side effects include:

• flushing
• abdominal discomfort
• nausea and vomiting
• breast tenderness
• headaches
• abnormal vaginal bleeding
• general fatigue
• hair loss
• visual symptoms

An important risk arises from the drug’s action on the brain that may lead to vision changes due to pituitary gland enlargement. Reports indicate potential visual disturbances after prolonged use, occurring in some cases within just a week. Immediate discontinuation and consultation with an ophthalmologist are imperative upon experiencing any vision changes.

Mood changes

Another critical side effect of Clomid is mood disturbances, with users occasionally exhibiting severe depression, anxiety, and aggression, among other behavioral changes. Nevertheless, clinical studies reflect that these side effects affect fewer than 1% of women.

Cost

Although Clomid requires a prescription for infertility treatment, it is widely obtainable online. Prices for clomiphene fluctuate, averaging between $50 to $100 for 100 tablets (25-50 mg).

Levels

Despite easy accessibility, all professional sports organizations strictly prohibit Clomid use. Detection in urine can occur for 5-12 days post-consumption, with advanced testing capabilities identifying steroids and their metabolites, raising suspicion of abuse.