Sunrise Extra Super Tadarise 10 tabs (40 + 60 mg/tab)

Tadalafil - Cialis

Tadalafil is a member of the phosphodiesterase type 5 (PDE5) inhibitors class, widely known by its trade name Cialis for treating erectile dysfunction, and Adcirca for pulmonary arterial hypertension.

Mechanism of Action

• Tadalafil inhibits the enzyme phosphodiesterase type 5 (PDE5), preventing the breakdown of cyclic guanosine monophosphate (cGMP).
• Increased nitric oxide (NO) release during sexual arousal boosts cGMP levels.
• This action relaxes smooth muscles in the blood vessels, enhancing blood flow to the penis for erection maintenance.

Indications

• This medication is chiefly prescribed for erectile dysfunction in men.
• Additionally, it’s effective for benign prostatic hyperplasiaet pulmonary arterial hypertension in the form of Adcirca.

Onset of Action

• Tadalafil typically takes effect within 30 minutes to 1 hour after administration.

Duration of Action

• Its effects can persist for up to 36 hours, earning it the nickname “weekend pill.”
• This allows men to maintain an erection throughout this duration when sexually stimulated.

Dosage

• The recommended dose for erectile dysfunction treatment is 10 mg or 20 mg, taken approximately 30 minutes before sexual activity.
• A standard dosage for BPH is generally 5 mg daily.

Effets secondaires

• Possible side effects include headache, facial flushing, indigestion (nausea, diarrhea), dizziness, muscle pain, and backache.
• Serious reactions are rare but can include sudden vision or hearing loss.

Dapoxetine

Dapoxetine is a medication aimed at treating premature ejaculation in men, marketed as Priligy.

Mechanism of Action

• As a selective serotonin reuptake inhibitor (SSRI), dapoxetine delays the reuptake of serotonin to enhance its availability in the brain.
• This boost in serotonin enhances control over ejaculation, leading to prolonged time before ejaculation.

Indications

• Dapoxetine is specifically indicated for men with premature ejaculation issues.
• It is suitable for those aged 18 to 64 facing rapid ejaculation challenges.

Onset of Action

• The effects of dapoxetine are generally felt within 1 to 2 hours post-consumption.

Duration of Action

• Effectiveness can last from 4 to 24 hours, depending on dosage and individual response.

Dosage

• The typical dapoxetine dose ranges from 30 mg to 60 mg, taken as needed.
• A starting dosage of 30 mg is common, with adjustments based on response.

Effets secondaires

• Common side effects may include dizziness, headache, nausea, drowsiness, fatigue, and dry mouth.
• Less frequently, hot flashes, increased anxiety, behavioral alterations, or changes in sexual function may occur.

Contre-indications

• Use of dapoxetine is contraindicated in patients with severe hepatic or renal impairments, significant heart conditions, epilepsy, bipolar disorder, or those on MAO inhibitors.
• Avoiding alcohol while on dapoxetine is crucial, as it can heighten side effects.