Hubei Clomid 30 tabs (50 mg/tab) EXPIRATION

Clomiphene Citrate - Clomid

Clomiphene citrate, commonly known as Clomid, is a powerful synthetic non-steroidal medication closely resembling estrogen. It is primarily utilized as an ovulatory stimulant. Due to its structural similarity to estrogen, it binds to the estrogen receptors in the hypothalamus, effectively misleading it into perceiving reduced estrogen levels. As a result, the hypothalamus stimulates the pituitary gland to secrete increased levels of gonadotropins, including FSH and LH, which encourage the ovaries or testes to augment estrogen or testosterone production.

This mechanism has proven effective for treating women with ovarian failure, promoting ovulation. However, extended use may raise concerns regarding ovarian cancer risk.

Farmakologija

Clomid is advised for women experiencing ovulatory dysfunction. Many women struggling with infertility are found to have irregularities in their ovulation cycles, including those with polycystic ovarian syndrome or unknown causes of amenorrhea. A thorough menstrual cycle assessment is essential before prescribing Clomid, ensuring that the origin of the issue is identified. Monitoring body temperature and conducting blood tests are vital for confirming ovulation.

Typically, Clomid treatment begins around day 5 of the cycle and continues for 3-6 cycles. Long-term treatment is discouraged.

Veikimo būdas

Clomid is renowned for its effectiveness. With proper dosage and short-term usage, it can benefit infertile women. Clomiphene mimics estrogen, interacting with estrogen receptors in the hypothalamus to block their activity, leading the brain to assume lower estrone levels. This, in turn, causes a surge in gonadotropins, hyperstimulating the ovaries to produce more estrogen, which is crucial for fertilization.

Indikacijos

Clomid is exclusively recommended for women with ovulatory dysfunction who also meet the following criteria:

• Not pregnant at the time of treatment.
• No ovarian cysts, confirmed via ultrasound.
• No vaginal bleeding; if present, thorough evaluation is required to rule out cancer.
• Normal liver function tests.
• While Clomid has shown success in female infertility, its effects on male fertility remain inadequately studied. Isolated cases in Europe and the USA report its utility in stimulating LH and FSH levels, leading to enhanced sperm count with minimal side effects noted. Nonetheless, there are concerns about potential long-term risks, such as testicular tumors and mild gynecomastia.

Clomiphene is a large, odorless molecule, soluble in various organic solvents and available in 50 mg tablets.

Patients must undergo a comprehensive evaluation for gynecological and endocrine disorders before starting Clomid. Ovulation typically occurs 5-10 days post-initiation of treatment, with sexual intercourse timed accordingly.

Clomid begins at a dosage of 50 mg/day for five days, adjustable for women who do not ovulate.

Kūno rengyba

Clomid is frequently misused by both amateur and professional athletes, often in conjunction with anabolic steroids, HCG, tamoxifen, and thyroid hormones. Unlike many anabolic steroids, Clomid does not suppress testosterone levels; it increases them by inducing higher LH levels.

Many anabolic steroids feature androgenic and anabolic properties, with some converted into estrogen via aromatase, leading to gynecomastia in bodybuilders. Therefore, Clomid is employed to prevent gynecomastia by blocking estrogen receptors, facilitating increased testosterone synthesis, benefitting athletes.

Clomid dozė sportininkams

Clomid is usually administered once daily. Bodybuilding experts suggest using it alone or alongside low-potency anabolic steroids. Athletes typically transition to Clomid after a steroid cycle to sustain testosterone levels and mitigate breast enlargement. Starting Clomid is recommended within 7-10 days after stopping steroids.

Many athletes report varying Clomid dosages, typically ranging from 50-100 mg/day for two weeks, with adjustments made if no effects are noted. After three weeks, Clomid use should cease, although proper medical guidance is scarce since it is not recommended for bodybuilding.

Šalutinis poveikis

When taken as advised, Clomid is generally safe, with most adverse reactions being mild and resolving after discontinuation. Common side effects include:

• Flushing
• Abdominal discomfort
• Nausea and vomiting
• Breast tenderness
• Headaches
• Abnormal vaginal bleeding
• Nuovargis
• Plaukų slinkimas
• Visual disturbances

Due to its interaction with the brain, one significant side effect involves vision changes stemming from overstimulation of the pituitary gland, potentially compressing the optic nerves, leading to issues like floaters or vision loss. Such symptoms typically arise after prolonged use but have occurred in some individuals after only a week or two. Immediate cessation of Clomid is recommended upon experiencing vision changes, with subsequent ophthalmologist consultation advised.

Mood Changes

Another prominent side effect is mood alterations. Prolonged Clomid use has been linked to behavioral issues, with reports of depression, anger, anxiety, and aggression. Other noted changes include paranoia, restlessness, and insomnia.

Despite these potential side effects, studies indicate they occur in less than 1% of women, and data on bodybuilders’ experiences is limited.

Išlaidos

While a prescription is needed for infertility treatment, Clomid is readily available online without one. Prices for 100 pills (25-50 mg) typically range from $50-100.

Lygiai

Clomiphene remains accessible for personal use, yet all professional sports organizations prohibit its usage. The substance is detectable in urine for 5-12 days post-administration. Advanced testing can identify its metabolites and assess testosterone-estrogen ratios, raising suspicion of abuse if certain thresholds are detected.