Sopharma Tamoksifēns 30 tabs (10 mg/tab)

Tamoksifēns – Nolvadex

Nolvadex is a powerful non-steroidal medication known for its remarkable anti-estrogen properties. By attaching itself to estrogen receptors, it effectively inhibits estrogen’s effects. This drug is primarily prescribed for specific types of breast cancer in both women and men. It also plays a crucial role in preventing breast cancer for women diagnosed with ductal carcinoma in situ, particularly those at elevated risk. Additionally, Nolvadex is under investigation for its efficacy in treating other forms of breast cancer.

Indikācijas

Nolvadex is indicated for women and men with metastatic breast cancer, particularly premenopausal women. It is often favored over surgical options and radiation. Patients with estrogen receptor-positive tumors see significant benefits from Nolvadex therapy, and it is indicated for adjuvant treatment post-surgery in women.

Dozēšana

Nolvadex comes in 10 mg and 20 mg tablets, as well as a 10 mg solution. The standard recommended dosage is 20 mg daily, easily taken orally, with or without food. For those with breast cancer, doses typically range from 20-40 mg daily, divided into 1-3 doses for amounts exceeding 20 mg. Bodybuilders often initiate treatment at 20 mg/day, increasing to 30 mg/day as needed, but long-term use is generally not advised beyond five years.

Bodybuilders

Nolvadex does not exhibit direct anabolic or androgenic effects; its benefits stem from blocking estrogen receptors. This blockade leads to increased Gonadotropins production, enhancing testosterone synthesis, which is responsible for its anabolic effects. Many bodybuilders use Nolvadex post-anabolic steroid cycles to counteract testosterone suppression and prevent ginekomastija and water retention, although some prefer Arimidex due to similar effects.

Nolvadex results in minimal weight gain alone, but assists in maintaining weight after anabolic steroid cycles and promotes testicular recovery during washout periods.

Sievietes

This medication is commonly prescribed to women battling metastatic breast cancer. Regular follow-ups with a physician are crucial, especially for women using Nolvadex for bodybuilding purposes. Notable side effects may include:

• asiņošana no maksts
• jauni krūšu dziedzeri
• abdominal fullness
• pelvic pain
• kāju pietūkums
• shortness of breath
• vision changes
• irregular menstruation

Regular breast examinations by healthcare professionals are essential, as complications—though rare—should not be overlooked. Female bodybuilders should be aware that oral contraceptive efficacy may be reduced when taking Nolvadex.

Overall Side Effects

Nolvadex is generally safe, with over 1-3% of women experiencing significant side effects. Common side effects for both genders include:

• karstuma viļņi
• kāju pietūkums
• altered taste
• genital itching
• depresija
• dizziness
• galvassāpes
• matu izkrišana
• maksts sausums
• nausea and vomiting
• kaulu sāpes
• klepus
• vēdera dobuma cramps
• ēstgribas zudums

Most side effects diminish after discontinuation.

Brīdinājumi

Be wary that Nolvadex may induce hypercalcemia in patients with breast cancer shortly after initiation. Instances of uterine cancer associated with Nolvadex have also been documented, along with risks of blood clots that could lead to pulmonary embolism. Rare complications include liver cancer and vision changes.

Pārdozēšana

Nolvadex is considered safe, with no reported overdose cases. Symptoms may not manifest for 4-6 days following excessive ingestion, including tremors, unsteady gait, dizziness, or irregular heart rate. Supportive treatment is the recommended course of action, with no lasting toxicity recorded.

Atklāšana

This medication is scrutinized by various sports organizations. While prescriptions may exist for females, males testing positive for Nolvadex face disqualification from competitive sports. The drug and its metabolites can remain traceable in urine for 3-4 weeks post-administration.

Izmaksas

Nolvadex is readily accessible, though not inexpensive, with an average price range of $1.50-$2.00 per pill. Although generic alternatives from Asia may be cheaper, their quality and purity remain questionable. Currently, no counterfeit Nolvadex products have been identified in the market.