Anfarm Hellas Clomiphene Citrate 24 tabs (50 mg/tab)

Clomiphene Citrate – Clomid

Clomiphene citrate, known as Clomid, is a synthetic, non-steroidal medication resembling estrogen. As an effective ovulatory stimulant, it binds to estrogen receptors in the hypothalamus, preventing the detection of actual estrogen levels, which prompts the pituitary to release more gonadotropins like FSH and LH. This elevation supports the increased production of estrogen and testosterone in the ovaries and testes, respectively. Clomid is particularly valuable for women facing ovarian failure and those needing to induce ovulation, although long-term use may heighten ovarian cancer risks.

Farmakologi

Clomid is prescribed for women experiencing ovulatory dysfunction. Women with fertility challenges often encounter disturbances in their ovulatory cycles, including those with polycystic ovarian syndrome or unknown causes of amenorrhea. A comprehensive evaluation of the menstrual cycle is crucial before Clomid is administered to pinpoint the underlying issues. Timely administration is vital; ovulation monitoring via body temperature and blood tests is essential.
Clomid typically begins around day 5 of the cycle and is recommended for 3-6 cycles, with long-term therapy not advised.

Virkemåte

Clomid serves as a potent pharmaceutical aid for infertile women, mimicking estrogen’s effects. It interacts with hypothalamic estrogen receptors, creating a false perception of low estrone levels. This activates a surge in gonadotropins, stimulating ovarian estrogen production—crucial for successful fertilization.

Indikasjoner

Clomid is specifically intended for women facing ovulatory dysfunction but must also meet these criteria:

• not pregnant at the time of treatment
• absence of ovarian cysts confirmed by ultrasound
• no vaginal bleeding, ensuring no underlying cancers
• normal liver function tests
• though not extensively studied for male infertility, Clomid sometimes assists men by enhancing LH and FSH, thus increasing sperm count; potential risks include testicular tumors and gynecomastia.
• appropriate prescription dosage for infertility

Clomiphene, a large molecule, dissolves in most organic solvents and is provided in 50 mg tablets. Patients must undergo a full work-up for gynecological and endocrine disorders prior to initiating Clomid. Ovulation is expected 5-10 days post-initiation, and intercourse should align with this timing.
Clomid is generally administered at 50 mg/day for 5 days, with dosage adjustments possible for those who do not ovulate.

Kroppsbygging

Athletes, both amateur and professional, often misuse Clomid alongside a range of other substances, including anabolic steroids and HCG. Unlike anabolic steroids, Clomid does not suppress testosterone levels; instead, it leads to increased testosterone through enhanced LH release.
Many anabolic steroids possess both androgenic and anabolic properties and can exert estrogenic effects, leading to gynecomastia. Clomid is employed to combat this by blocking estrogen receptors, ultimately reducing gynecomastia associated with steroids.
Moreover, through hypothalamic blockage of estrogen receptors, Clomid promotes a surge in LH and FSH, enhancing sex hormone synthesis, including testosterone—beneficial for athletes. Some bodybuilders utilize Clomid exclusively for its anabolic effects while others combine it with steroids and growth hormones.

Clomid-dosering for idrettsutøvere

Clomid is typically administered once daily. Bodybuilding experts recommend its use either alone or with low-potency anabolic steroids, often transitioning to Clomid within 7-10 days post-steroid use for testosterone surges and to prevent breast enlargement. Athlete dosages tend to vary, with many taking 50-100 mg/day for two weeks, potentially increasing to 100 mg/day if no effects are noted, then discontinuing by the third week. There is limited physician guidance available regarding Clomid for bodybuilding, making it vital to seek advice from fertility specialists if needed.
The duration of Clomid administration remains unclear, and prolonged usage is generally discouraged.

Bivirkninger

At standard doses for limited durations, Clomid is generally safe. Most side effects are transient and resolve upon treatment cessation. Common adverse effects include:

• spyling
• abdominalt ubehag
• nausea and vomiting
• ømhet i brystene
• hodepine
• unormal vaginal blødning
• generell utmattelse
• hårtap
• visual disturbances

Due to its action on the brain, one concerning side effect is related to visual changes, as excessive stimulation of the pituitary gland may lead to increased pressure on optic nerves. Various vision changes, ranging from floaters to partial vision loss, may arise, particularly after prolonged use; caution is advised in driving or operating machinery. These symptoms often reverse upon discontinuation of Clomid, warranting immediate medical consultation with an ophthalmologist.

Humørsvingninger

Clomid can also induce mood alterations; long-term users may report significant emotional disturbances such as depression, aggression, anxiety, or insomnia. Despite these serious side effects, studies indicate that they appear in less than 1% of women.

Kostnader

Though a prescription is needed for Clomid for infertility treatment, it is readily available online without one, with costs typically ranging between $50 and $100 for 100 pills (25-50 mg).

Nivåer

Clomid’s availability is notable, but all major sports organizations prohibit its use in professional athletics. The substance can remain detectable in urine for 5-12 days post-use, with advanced testing capable of measuring testosterone and estrogen levels and their metabolites.
When certain ratios of these hormones are detected, clomiphene abuse is suspected.