Hilma Biocare Tadalafil C20 10 tabs (20 mg/tab)

Tadalafil – Cialis

Tadalafil is a phosphodiesterase type 5 (PDE5) inhibitor, primarily marketed under the brand names Cialis for erectile dysfunction treatment and Adcirca for pulmonary arterial hypertension.

Mechanism of Action

• Tadalafil inhibits the enzyme PDE5, preventing the breakdown of cyclic guanosine monophosphate (cGMP).
• Increased nitric oxide (NO) release during sexual arousal raises cGMP levels.
• This results in relaxation of smooth blood vessel muscles, enhancing blood flow to the penis and facilitating erection achievement and maintenance.

Indikationer

• Used predominantly for treating erectile dysfunction in men.
• Also prescribed for benign prostatic hyperplasia (BPH) and pulmonary arterial hypertension.

Onset of Action

• Rapid onset typically occurs within 30 minutes to 1 hour post-administration.

Duration of Action

• Effects can persist up to 36 hours, earning it the name “weekend pill.”
• This allows for the possibility of erection during this period with sexual stimulation.

Dosering

• Common doses for erectile dysfunction are either 10 mg or 20 mg, taken as needed about 30 minutes before sexual activity.
• For managing BPH, a daily dose of 5 mg is standard.

Biverkningar

• Common reactions may include headache, facial flushing, indigestion, dizziness, muscle discomfort, and backache.
• Serious side effects like sudden vision or hearing loss can occur but are rare.

Kontraindikationer

• Avoid taking Tadalafil with nitrates (e.g., nitroglycerin) due to the risk of severe blood pressure drops.
• Contraindicated in individuals with serious heart conditions or a recent history of myocardial infarction or stroke.